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EC number: 220-971-6 | CAS number: 2950-43-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results for the surrogate substance, as acute LC50 (fish) 7.2 mg/L were estimated (NAPM, 1974).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 7.2 mg/L
Additional information
Short-term toxicity to fish
Since data for the test substance hydroxylamine-O-sulphonic acid (CAS 2950-43-8) are not available, results of the surrogate substance bis(hydroxylammonium) sulfate (CAS 10039-54-0) are used in a reliable read-across approach to evaluate the test substance.
There are only a few publications available on the acute toxicity to fish. In a publication of the National Association of Photographic Manufactures (NAPM 1974) among other substances the effects of bis(hydroxylammonium)sulphate on Pimephales promelas were tested in a static system for 96 hours according to standard procedures outlined in Standard Methods, 13th Edition (ASTM, American Society for Testing and Materials). The LC50 determined in this test was 7.2 mg/L. Basic information about the test is given (dilution water was examined, daily monitoring of pH and dissolved oxygen was conducted). The study is carried out according to an old guideline and no concentrations were measured. Due to these facts, this study was considered as not reliable in EU-RAR draft 2008. Nevertheless, test results are consistent with results of other aquatic tests, as shown in this risk assessment and may therefore be taken into account in the aquatic hazard assessment.
In a publication from 1972 (Fletcher & Addison) about “some aspects of of the chemistry and acute toxicity of the iron ore flotation agent dimethyl ammonium alkyl hydroxamate and some related compounds to brook trout” lethal periods of DMAH and some related components were determined. The brook trout Salvelinus fontinalis was used as test organism. The high toxicity of hydroxylamine hydrochloride for fish was confirmed by an EC50 of 6 µL/L after 142 hours under flow-through conditions. In a parallel test for 80 hours of semi-static exposure the EC50 was 10 µL/L. However, not bis(hydroxylammonium)sulphate was tested. Hence the results are only of indicative value for this risk assessment.
Furthermore, in a static test, performed according to an old German guideline with only 48 hours test duration, an LC50 (48h) of 6.67 mg/L was observed for for Bis(hydroxylammonium)sulphate. However, due to insufficient documentation, the test is not valid. Nevertheless, since this result is in accordance with those of other studies, it may be used as supportive information (BASF, 1976).
In addition to that a screening report is available. In this study (Applegate et al. 1957) 4,346 chemicals were screened for their acute toxicity for rainbow trout, bluegill sunfish and sea lamprey for 24 hours of static exposure. The intention of the study was a screening for a substance toxic for lamprey but not toxic for fish. The study is not useful to determine effective concentrations.
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