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EC number: 800-153-0 | CAS number: 1313206-64-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 5.12 µg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1.5 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.512 µg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 0.34 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 2.38 mg/kg sediment dw
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 238 µg/kg sediment dw
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 10 mg/kg soil dw
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Due to intrinsic properties of amine containing cationic surfactants river water ecotoxicity tests deliver reproducible test results with limited uncertainty. As river water has a mitigating effect on ecotoxicity due to sorption of the amines to and suspended matter a factor of 10 should be applied to correct for the lower ecotoxicity observed.
Conclusion on classification
The environmental fate and ecotoxicological properties of the Amines, N-(C16-18 and C18unsatd. alkyl)trimethylenedi-, diacetates (CAS 1313206-64-2) are equivalent to the properties of diamines. Indeed, it can be expected that the ecotoxicity of the diamines acetate in aqueous solution is not related to acetates therefore the ecotoxicological data of the diamines can be used for the registered salt. For more details, please see to the read-across justification document attached in the corresponding aquatic Endpoint Study Records.
If no data are available on a salt, effects may be read-across from the anion or cation, whichever has the most toxic effect. As the effect endpoints were related to only one of the ions, therefore the classification of the salt use the effect concentration multiplied by the molecular weight ratio of the substance (according REACH guidance document R7b v4, June 2017 p 81).
The classification of the registered substance according to CLP regulation 1272/2008 EC is aquatic acute category I, H400 M=10 and aquatic chronic category II defined by the environmental data detailed below.
The classification has been established considering that the substance is rapidly biodegradable and have a low lipophilic behaviour with an experimental value of log Kow <4.
Aquatic acute category
96h-LC50 fish was 1,5 mg/L
48h-EC50 invertebrates was 0,395 mg/L (corrected by a factor 10 due to river water testing, that yields to EC50 = 0,0395 mg/L).
72h-ErC50 algae was 0,69 mg/L (corrected by a factor 10 due to river water testing, that yields to ErC50 = 0.069 mg/L)
As all ecotoxicity values (corrected and uncorrected) are below 1 mg/L. Based on these results it is proposed to classify the Amines, N-(C16-18 and C18-unsatd. alkyl)trimethylenedi-, diacetates as Acute Category 1
The corresponding M-factor is 10 based on the EC50 of 39.5 µg/L (21 d EC50 parental daphnia of 395 µg/L and applying an additional correction factor of 10 for mitigation).
The registered substance is therefore considered Aquatic Acute Category I, H400 M=10.
Aquatic chronic category
Long-term test result for fish is not required.
21d-NOEC for daphnia was 1 mg/L (corrected by a factor 10 due to river water testing, that yields 0,1 mg/L)
72h-EC10 for algae was 0,26 mg/L (corrected by a factor 10 due to river water testing, that yields 0,026 mg/L)
When chronic toxicity data are available these should be used for classification for chronic aquatic hazard. Considering the lower sensitivity of fish it is considered justified to use the long-term daphnia and algae test results for the chronic classification. The lowest EC10 value obtained is for Algae, ErC10 = 256 µg/L. Correcting this value for mitigation (river water) with the realistic worst-case correction factor of 10 leads to EC10 for classification of 25.6 µg/L. Thus the substance is classified as Chronic Category 2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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