Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 306-111-3 | CAS number: 96152-40-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Skin irritation = Not irritating, male rabbit, OECD 404, EU Method B.4, Goldet and Guillot, 1986
Eye irritation = Not irritating, male rabbit, OECD 405, EU Method B.5, Goldet and Guillot, 1986
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin
The skin irritation potential of the test material was determined in accordance with standardised guidelines OECD 404 and EU Method B.4. During the study, six rabbits received a single four hour application of 0.5 mL test material and were assessed for the following 72 hours for any signs of skin irritation. Very slight erythema was seen in all animals approximately one and 24 hours after application. Very slight erythema persisted 72 hours after application in two of the animals. Very slight erythema persisted 48 hours application in one animal. There were no other signs of skin irritation noted during the study. No signs of edema were recorded.
Eye
The eye irritation potential of the test material was determined in accordance with standardised guidelines OECD 405 and EU Method B.5. During the study, approximately 0.1 mL test material was instilled into the right conjunctival sac of each of six rabbits; the left eye remained untreated and served as the control. The animals were assessed for up to 72 hours following test material administration to determine the grade of ocular reaction. There were no corneal effects. Conjunctival effects consisted of slight redness and slight chemosis in all animals up to 24 hours after application. In addition, one animal had slight erythema approximately 48 hours after application. In addition, slight iridial effects were noted in all animals 1 hour after instillation and persisted for 24 hours in 4 animals and for 48 hours in 1 animal. All signs of irritation had completely resolved within 72 hours of application.
Both studies presented to assess the irritation and corrosion potential of the test material were performed in line with accepted standardised guidelines with a high standard of reporting. Both studies were assigned a reliability score of 1 in accordance with the criteria for assessing data quality as outlined in Klimisch (1997).
Justification for selection of skin irritation / corrosion endpoint:
Only one study is available.
Justification for selection of eye irritation endpoint:
Only one study is available.
Justification for classification or non-classification
Skin
In accordance with with criteria for classification as defined in Annex I, Regulation 1272/2008, the test material does not require classification for skin irritation.
Eye
In accordance with the criteria for classification as defined in Annex I, Regulation 1272/2008, the test material does not require classification for eye irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.