Disodium 6-hydroxy-5-[(4-sulphonatophenyl)azo]naphthalene-2-sulphonate

Short-term toxicity to aquatic invertebrates

Description of key information

Determination of the inhibition of the mobility of daphnids was carried out with the substancedisodium 6-hydroxy-5-[(4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonateaccording to OECD Guideline 202.

The test substance was tested at the concentration 100 mg/L. 0% Daphnia were immobilised at the end of the test.

The median effective concentration (EC50) for the test substance,disodium 6-hydroxy-5-[(4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate, in Daphnia magna was determined to be > 100 mg/L for immobilisation effects.

This value indicates that the substance is not likely to be hazardous to aquatic invertebrates as per the CLP criteria.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

100 mg/L

Additional information

No. of studies were reviewed for Short-term toxicity to aquatic invertebrate from reliable sources having Klimisch rating 1, 2 and 4. 

The summary of the results are presented below   

Sr.No	Endpoint	Effect values	Basis for effects	Duration	Species	CAS No.	Sources
1.	EC50	100 mg/L	Intoxication	48 hrs.	Daphnia magna	Target cas no.2783-94-0	test data
2.	EC50	486.5mg/L	-	48 hrs.	Daphnia magna	Target cas no.2783-94-0	Predicted data from ECOSAR
3.	LC50	295 mg/L	-	48 hrs.	Daphnia magna	Read across substance cas no.25956-17-6	Predicted data from ECOSAR

 

Based on the studies summarized in the above table for the target substance disodium 6-hydroxy-5-[(4-sulphonatophenyl)azo]naphthalene-2-sulphonate and the read across substance, the endpoint value was found to be EC50 = >100 mg/L to486.5mg/L and LC50=295 mg/L in a 48 hrs.; on the basis of Intoxication effect. Based on the above weight of evidence values, the substance it is concluded that the test substance dose not qualifies for the aquatic toxicity.