Registration Dossier
Registration Dossier
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EC number: 243-231-4 | CAS number: 19694-10-1
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1988
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: study was carried out according to OECD 209 but only results reported
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1989
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-amino-4-chlorobenzamide
- EC Number:
- 243-231-4
- EC Name:
- 3-amino-4-chlorobenzamide
- Cas Number:
- 19694-10-1
- Molecular formula:
- C7H7ClN2O
- IUPAC Name:
- 3-amino-4-chlorobenzamide
Constituent 1
Test organisms
- Test organisms (species):
- activated sludge
Results and discussion
Effect concentrationsopen allclose all
- Dose descriptor:
- EC10
- Effect conc.:
- 323 mg/L
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Remarks on result:
- other: No numbers for duration given in the brief report only EC values, but test performed according to OECD209
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Remarks on result:
- other: No numbers for duration given in the brief report only EC values, but test performed according to OECD209
- Dose descriptor:
- EC100
- Effect conc.:
- > 1 000 mg/L
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Remarks on result:
- other: No numbers for duration given in the brief report only EC values, but test performed according to OECD209
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The tested substance is expected to be not toxic to bacteria in a biodegradation test. EC50 value amounts to > 1000 mg/L.
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