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EC number: 939-600-0 | CAS number: 1471316-27-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Sediment toxicity
Administrative data
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- GLP guideline study with acceptable restrictions: The salinity for 100mg/L, third replicate, rose above guideline criterion at day 5 by 1‰ and day 10 by 2‰. As there were no mortalities in this replicate, this is not thought to have affected the result. 22 organisms was recovered from beaker 320c mg/kg, this is a greater number than should have been added at test initiation (20) therefore the replicate was excluded from the analysis.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OSPARCOM guidelines (2006) Part A. A sediment bioassay using an amphipod Corophium sp.
- Deviations:
- yes
- Remarks:
- The salinity for 100mg/l, third replicate, rose above guideline criterion at day 5 by 1‰ and day 10 by 2‰.
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Alcohols, C16-18 (even numbered) and C18 unsaturated, propoxylated, < 2.5 PO
- EC Number:
- 939-600-0
- Cas Number:
- 1471316-27-4
- Molecular formula:
- not applicable, UVCB
- IUPAC Name:
- Alcohols, C16-18 (even numbered) and C18 unsaturated, propoxylated, < 2.5 PO
- Details on test material:
- - Name of test material (as cited in study report): Tallow alkyl polyglycol ether, CAS 70955-07-8
- Physical state: yellowish liquid
- Analytical purity: 99.7%
- Lot/batch No.: 0008563697
- Expiration date of the lot/batch: 2 July 2014
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Vehicle:
- no
- Details on sediment and application:
- Test sediment: Sediment for use in toxicity testing was collected from a point adjacent to the site of Corophium collection. On return to the laboratory, the sediment was wet-sieved through 0.6 mm mesh to remove larger infaunal organisms and Corophium within the test size range, and allowed to settle in tall polyethylene containers. After settling, the supernatant water was decanted and the sediment stored at approximately 4 +- 2 °C, until required for testing.
Particle size analysis characterised the sediment as well-sorted, fine sand with a silt/clay content of 31.6% by weight. Median particle diameter was 100 µm. The organic material content was estimated from weight loss on ignition to be 2%. Immediately before the initiation of the test, the sediment was thoroughly homogenised and a representative sample taken for wet and dry weight determination. The ratio of wet weight to dry weight was subsequently used to convert nominal exposure concentrations on a wet weight basis to nominal exposure concentrations on a dry weight basis.
Test organisms
- Test organisms (species):
- Corophium volutator
- Details on test organisms:
- The test population of Corophium volutator was collected from an uncontaminated site in Orkney. The site location at Bay of Suckquoy, Toab, Orkney was chosen because of its high natural densities of Corophium. Initial parameters of the holding water were recorded upon arrival at the Opus laboratory. Specimens were gently sieved from their native sediment and held in plastic containers (approximately 5 L capacity) containing some ambient water, with a small amount of detritus, until transfer to the laboratory. On return to the laboratory, the Corophium were transferred in ambient water to polythene tanks of approximately 200 L capacity, gentle aeration was supplied. The tanks were held at approximately 15±2 °C.
The stock animals were gradually acclimated from the ambient salinity of less than 5‰ to that of undiluted seawater (approximately 35‰) in increments of approximately 10‰ per day. Once acclimation is complete, the stock tanks were maintained under semi-static conditions until the initiation of the test. The holding period in the laboratory is between 3 and 14 days. Sufficient detrital material is retained in each tank to provide food and some bottom cover, but not of a density that prevents daily observation of mortality and morbidity. Dead or impaired animals are removed when
observed. Specimens of approximately 5 mm in body length (excluding rostrum) were used in the toxicity tests.
Study design
- Study type:
- laboratory study
- Test type:
- static
- Water media type:
- saltwater
- Type of sediment:
- natural sediment
- Limit test:
- no
Exposure duration
- Duration:
- 10 d
- Exposure phase:
- total exposure duration
Test conditions
- Test temperature:
- 14.1 °C
- pH:
- 7.97 - 8.08
- Dissolved oxygen:
- > 85% saturation
- Salinity:
- 36 - 40 ‰
- Nominal and measured concentrations:
- Nominal: 10, 100, 320, 1000 and 10000 mg/kg
- Details on test conditions:
- Tests were conducted in 1 litre capacity glass beakers each containing 2 cm depth (approximately 150 ml) of amended sediment and 850 ml of overlying seawater (1 μm filtered ultra violet treated seawater). Test beakers were maintained in a controlled temperature room for a test period of 10
days. Three replicates were prepared for each test concentration; controls are replicated five times. The beakers were assigned positions within the test area, arranged in rows of three to five and spaced to maintain effective separation of different treatments. Each row was covered with a rectangular sheet of perspex perforated with a small hole above the centre of each beaker. Aeration was provided and a stream of air bubbles was released at a depth of approximately 6 cm. Twenty animals were added to receiving vessels in two groups of ten and then dispensed into a test vessel. Sixty organisms were exposed in total per concentration and one hundred in five vessels for controls. The final level of water in each test vessel was marked with a permanent marker.
Salinity is maintained at ±4 ppt from the initial 0h figure during the test. A 5 mm drop in water level is equivalent to ~2 ppt increase in salinity. Any visible signs of animals on the sediment surface whether alive or dead were recorded. At the end of the test period, the contents of each beaker were gently sieved through a 0.6 mm mesh, and all surviving animals separated and counted. Missing animals were counted as dead; early mortalities will either have been consumed by survivors or have decomposed during the test period. - Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 10 d
- Dose descriptor:
- LC50
- Effect conc.:
- 7 227.57 mg/kg sediment dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
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