Registration Dossier
Registration Dossier
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EC number: 200-076-7 | CAS number: 51-03-6
Toxicity to birds
Administrative data
- Endpoint:
- short-term toxicity to birds: acute oral toxicity test
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EPA OPP 71-1 (Avian Acute Oral Toxicity Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
- EC Number:
- 200-076-7
- EC Name:
- 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
- Cas Number:
- 51-03-6
- Molecular formula:
- C19H30O5
- IUPAC Name:
- 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
Constituent 1
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- Colinus virginianus
Study design
- Total exposure duration (if not single dose):
- 14 d
- No. of animals per sex per dose and/or stage:
- 60
Each dosage group was assigned two pens. One pen contained five males and the other five females
[800 cm2 / bird]
Results and discussion
Effect levelsopen allclose all
- Duration (if not single dose):
- 14 d
- Dose descriptor:
- NOEC
- Effect level:
- 486 mg/kg bw
- Conc. / dose based on:
- not specified
- Basis for effect:
- not specified
- Duration (if not single dose):
- 14 d
- Dose descriptor:
- LC50
- Effect level:
- > 2 250 mg/kg bw
- Conc. / dose based on:
- not specified
- Basis for effect:
- not specified
Applicant's summary and conclusion
- Conclusions:
- The acute oral LD50 for northern bobwhite quail exposed to PBO as a single oral dose was determined to be greater than 2250 mg a.i./kg bw. The NOEL was 486 mg a.i./kg bw, based on the loss in body weight among females at 810 mg a.i./kg during the first three days only.
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