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EC number: 234-217-9 | CAS number: 10599-90-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.98 µg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no emission to STP expected
Sediment (freshwater)
- Hazard assessment conclusion:
- no exposure of sediment expected
Sediment (marine water)
- Hazard assessment conclusion:
- no exposure of sediment expected
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.181 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
Based on the available data, monochloramine is considered as rapidly degradable and not potentially bioaccumulable.
1) Classification and labelling for monochloramine as pure substance:
1.1) According to the DSD Regulation, Directive 67/548/EC
Acute toxicity:
The lowest L(E)C50s obtained were between 0.01 and 1 mg/L. The lowest L(E)C50 was 11.8 µg/L for theC. dubia(Farrell et al 2001).
Therefore, the monochloramine is considered to be “very toxic to the aquatic organisms”.
Monochloramine is classified as :R50 "very toxic to aquatic organisms" and labelled N.
Chronic toxicity:
Monochloramine is not classified as hazardous to the aquatic environment since it is considered as rapidly degradable and not potentially bioaccumulable.
Monochloramine is classified as: not classified
1.2) According to the CLP Regulation, Regulation (EC) No 1272/2008,
Acute toxicity:
The lowest L(E)C50s obtained were between 0.01 and 1 mg/L. The lowest L(E)C50 was 11.8 µg/L for theC. dubia (Farrell et al 2001).
Therefore, the monochloramine is considered to be “very toxic to the aquatic organisms”.
Monochloramine is classified as:"acute env. tox. cat. 1" and labelled "H400; Very toxic to aquatic life» and with an M-Factor of 10.
Chronic toxicity:
For CLP regulation,classification is based on the lowest EC10 obtained on Danio rerio and on the rapid degradability and not potentially bioaccumulable properties.The lowest EC10 was 9.8 µg/L (Daniel Gilberg (2012)). Thus,monochloramine is considered to be “very toxic to the aquatic life with long lasting effect”
Monochloramine is classified as:"Chronic env. tox. cat. 1» and labelled "H410 Very toxic to aquatic life with long lasting effect ") and with an M-factor of 1.
Overview of classification and labellingfor monochloramine as pure substance
In a context of DSD regulation,Directive 67/548/EC: N;R50
In the context of CLP regulation: Regulation (EC) No 1272/2008:
- “acute env. tox. cat. 1" and labelled "H400; Very toxic to aquatic life» and with an M-Factor of 10.
- “Chronic env. tox. cat. 1» and labelled "H410; Very toxic to aquatic life with long lasting effect» and with an M-factor of 1.
2) Classification and labelling for a mixture of monochloramine of concentration between 1% (10 g/L) and 0.25% (2.5 g/L):
2.1) According to the DPD Regulation, Directive 1999/45/EC:
Acute toxicity:
The mixture at 1% of monochloramine contain less than 2.5% (classification threshold for 0.01 < L(E)C50=0.0118 mg/L ≤ 0.1)of ingredient classified as very toxic to aquatic organisms (N ; R50), therefore the mixture at 1% of monochloramine is not classified for acute toxicity.
Chronic toxicity :
As monochloramine as pure substance is not classified for chronic toxicity, the mixture at 1% of monochloramine is not classified for chronic toxicity
2.2) According to the CLP Regulation, (EC) No 1272/2008 (CLP):
Classification was performed with the summation method.
Acute toxicity:
The sum of the concentration in % of the ingredient classified as acute Category 1 x M has to be ≥ 25% :
1% x 1 = 1% i.e. < 25%, thus the mixture is not classified for acute toxicity.
Chronic toxicity :
- The sum of the concentration in % of the ingredient classified as chronic Category 1 x M has to be ≥ 25%:
1% x 1 = 1% i.e. < 25%, thus the mixture is not classified as chronic toxicity category 1.
- (M x 10 x sum in % of the ingredient classified as chronic Category 1) + sum in % of the ingredient classified as chronic Category 2 has to be ≥ 25%:
(1 x 10 x 1%) + 0 = 10% i.e. <25%, thus the mixture is not classified as chronic toxicity category 2.
Formixture of monochloramineconcentration at 1%
- (M x 100 x sum in % of the ingredient classified as chronic Category 1) + (10 x sum in % of the ingredient classified as chronic Category 2) + sum in % of the ingredient classified as chronic Category 3 has to be ≥ 25%:
(1 x 100 x 1%) + 0 + 0 = 100% i.e. ≥ 25%, thus the mixture is classified as chronic toxicity category 3.
For mixture of monochloramineconcentration at 0.25%
- (M x 100 x sum in % of the ingredient classified as chronic Category 1) + (10 x sum in %of the ingredient classified as chronic Category 2) + sum in % of the ingredient classified as chronic Category 3 has to be ≥ 25%:
(1 x 100 x 0.25%) + 0 + 0 = 25% i.e. ≥ 25%, thus the mixture is classified as chronic toxicity category 3.
Overview of classification and labellingfor a mixture of monochloraminebetween 1% and 0,25%:
In a context of DPD regulation,1999/45/EC: not classified
In the context of CLP regulation: Regulation (EC) No 1272/2008:
- "Chronic env. tox. cat. 3" ("H412; harmful to aquatic life with long lasting effect ")
3) Classification and labelling for a mixture of monochloramine at less or equal to 0 .0003% (
≤
3 mg/L):
3.1) According to the DPD Regulation, Directive 1999/45/EC:
Acute toxicity:
The mixture at 0.0003% of monochloramine contain less than 2.5% (since 0,01 < L(E)C50=0.0118 mg/L ≤ 0,1) of ingredient classified as very toxic to aquatic organisms(N ; R50), thereforethe mixture at 0.025% of monochloramine is not classified for acute toxicity.
Chronic toxicity:
As monochloramine as pure substance is not classified for chronic toxicity, the mixture at 1% of monochloramine is not classified for chronic toxicity
3.2) According to the CLP Regulation, (EC) No 1272/2008 (CLP):
Classification was performed with the summation method.
Acute toxicity:
The sum of the concentration in % of the ingredient classified as acute Category 1 x M has to be ≥ 25%:
0.0003% x 10= 0.003% i.e. < 25%, thus the mixture is not classified for acute toxicity.
Chronic toxicity :
- The sum of the concentration in % of the ingredient classified as chronic Category 1 x M has to be ≥ 25%:
0.0003% x 1 = 0.0003% i.e. < 25%, thus the mixture is not classified as chronic toxicity category 1.
- (M x 10 x sum in % of the ingredient classified as chronic Category 1) + sum in % of the ingredient classified as chronic Category 2 has to be ≥ 25%:
(1 x 10 x 0.0003%) + 0 = 0.003% i.e. < 25%, thus the mixture is not classified as chronic toxicity category 2.
- (M x 100 x sum in % of the ingredient classified as chronic Category 1) + (10 x sum in % of the ingredient classified as chronic Category 2) + sum in % of the ingredient classified as chronic Category 3 has to be ≥ 25%:
(1 x 100 x 0.0003%) + 0 + 0 = 3% i.e.
<
25%, thus the mixture is not classified as chronic toxicity category 3.
Overview of classification and labellingfor a mixture of monochloramine at 0.0003%:
In a context of DPD regulation,1999/45/EC: not classified
In the context of CLP regulation: Regulation (EC) No 1272/2008: not classified
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