Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 421-320-0 | CAS number: 118289-55-7 CP-89,575
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 5 March - 18 June 1996
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: EC Directive 92/69/EEC, Method A6 (flask stirring method).
- Principles of method if other than guideline:
- Distilled water_(SO ml) and test substance (ca 0.1 g) were combined in each of six conical flasks. The flasks were firmly stoppered and the contents stirred at 30°C ± 0.5°C prior to equilibration at the test temperature of20°C ± 0.5°C.
The contents of the flasks were stirred for the following times:
Test Pre-equilibration at 30°C Equilibration at 20°C
IA, IB 3 days 1 day
2A,2B 2 days I day
3A,3B 1 day 1 day
A blank of distilled water was run concurrently with all the tests. - GLP compliance:
- yes
- Type of method:
- flask method
Test material
- Reference substance name:
- 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one
- EC Number:
- 421-320-0
- EC Name:
- 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one
- Cas Number:
- 118289-55-7
- Molecular formula:
- Hill formula: C10 H9 Cl2 N O CAS formula: C10 H9 Cl2 N O
- IUPAC Name:
- 6-chloro-5-(2-chloroethyl)-2,3-dihydro-1H-indol-2-one
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Intended use:Pharmaceutical intermediate
Purity:99.9%
Date received: 2 February 1996
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 3.84 mg/L
- Temp.:
- 20 °C
- Remarks on result:
- other: pH Data was not available
- Details on results:
- No peaks were observed at the characteristic retention volume of the test substance in the blank solutions, showing that the analytical procedure was free from interferences
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of CP-89,575 has been determined as:
3.84 X 10"3 g/1 at 20°C
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
