Shale oil pitch

Repeated dose toxicity: inhalation

Administrative data

Endpoint:

short-term repeated dose toxicity: inhalation

Type of information:

experimental study

Adequacy of study:

key study

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Data source

Reference

Reference Type:

publication

Title:

Unnamed

Year:

2011

Report date:

2011

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 422 (Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test)

Deviations:

yes

Test guideline 2

Qualifier:

according to guideline

Guideline:

other:

Deviations:

yes

Limit test:

no

Test material

Test material information

Constituent 1

Test animals

Species:

rat

Strain:

Wistar

Sex:

male/female

Administration / exposure

Route of administration:

inhalation

Type of inhalation exposure:

nose only

Results and discussion

Effect levels

1

Dose descriptor:

NOAEC

Effect level:

100.1 mg/m³ air (analytical)

Based on:

test mat.

Sex:

male

Basis for effect level:

other:

2

Dose descriptor:

NOAEC

Effect level:

30 mg/m³ air (analytical)

Based on:

test mat.

Sex:

female

Basis for effect level:

other:

Target system / organ toxicity

Critical effects observed:

not specified