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Diss Factsheets
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EC number: 480-390-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
Description of key information
29.1 % of the test material was determined to be less than 100 µm in size; less than 0.1 % of the test material was determined to be less than 10.0 µm in size, OECD 110, O'Connor & Woolley (2007).
Additional information
The particle size distribution of the test material was investigated in a study which was conducted under GLP conditions and in accordance with the standardised guideline OECD 110, using a cascade impactor.
Particle size distribution data obtained during the study differed from particle size distribution data which had already been generated using a laser diffraction method.
The discrepancy between the particle size distribution data as generated by laser analysis (a D10 value of 4.3 µm, a D50 value of 6.9 µm and D90 value of 10.7 µm) and that obtained within this study can be attributed to the different techniques employed. Whereas the laser diffraction data may remain an accurate reflection of the actual particle size of individual particles, the cascade impactor technique addresses the equivalent aerodynamic diameter of the particles. The sedimentation technique applied to inhalation risk assessment is dependent on not only the size and shape of the particles, but also their density. The extremely high relative density value of 4.63 for the test material would account for the discrepancy between the two techniques. Thus a particle size of small diameter but high density would result in a much higher equivalent aerodynamic diameter when addressing the potential for penetration of the airways and lungs due to rapid sedimentation under the influence of gravity. In addition, the test material was observed to be a non-free flowing powder, which did not readily form an aerosol, and thus the test material did not freely exist as individual particles.
Under the conditions of the study 29.1 % of the test material was determined to be less than 100 µm in size; less than 0.1 % of the test material was determined to be less than 10.0 µm in size.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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