Registration Dossier

Guidance on Safe Use

Guidance on Safe Use

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Administrative data

First-aid measures

Emergency measure - Inhalation: Remove the affected person in fresh air, loosen clothing as
necessary to assist with breathing. Seek medical attention.
Emergency measure - Eyes: Immediately wash out eyes with large amounts of water.
Continue irrigation for at least 15 minutes, separating the
eyelids (with fingers) to ensure complete irrigation of the
affected eye(s). Seek medical attention.
Emergency measure - Skin: Remove all contaminated clothing and wash affected areas
with copious amounts of water. Seek medical attention.
Emergency measure - Ingestion: Rinse out mouth with plenty of water. Seek medical

Fire-fighting measures

Recommended extinguishing agent: Use appropriate medium for underlying cause of fire. (eg.
carbon dioxide, dry chemical or foam)

Product arising from burning: carbon monoxide

carbon dioxide

Nefazodone II will not undergo hazardous polymerisation

Product determined by test: N

Protective equipment: full (impervious) clothing, with self-contained breathing

Accidental release measures

Emergency measures in case of spillage: Wear full protective clothing: overalls, rubber boots and
gloves, eye protection and a self-contained respirator.
Sweep up spilled material, minimising dust? Transfer solid
waste to sealed containers and wash spillage site with

Handling and storage

Handling: Use in well ventilated areas. Local exhaust ventilation and
careful use are recommended to minimise dust generation.

wear eye protection, overall and rubber gloves, and suitable
respiratory protection (approved to EN 136 standard). Wash
thoroughly after use.

Storage: Store in sealed, unbreakable containers in a cool dry place.

Transport information

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Marine transport (IMDG)

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Air transport ICAO/IATA

Transport: No UN number has been assigned. Use normal procedures for
transport of industrial chemicals not considered hazardous
for transport.
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Exposure controls / personal protection

Stability and reactivity

Danger other than fire: None known

Chemical reaction with water: None known

Disposal considerations

Industry - Possibility of recovery/recycling: Nefazodone II is consumed in the drug synthesis reaction in
which it is employed. Significant residual levels in reactor
effluent are not expected. No practical method of recovery
or recycling is known.

Industry - Possibility of neutralisation: No method of chemical neutralisation is known.

Industry - Possibility of destruction: controlled discharge: Not recommended.

Industry - Possibility of destruction - incineration: Acceptable provided that a closed cycle incinerator with
scrubbers is employed.

Industry - Possibility of destruction - water purification: Not recommended.

Industry - Possibility of destruction - other: Not recommended.

Public at large - Possibility of recovery/recycling: Nefazodone II is not intended for public use.