Registration Dossier
Registration Dossier
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EC number: 929-442-0 | CAS number: 1040871-35-9
Endpoint summary
Administrative data
Description of key information
The in-vivo acute dermal and the eye irritation of the test substance Reaction mass of iso-tridecyl 3-mercaptopropionate and iso-dodecyl 3-mercaptopropionate were determined in GLP laboratory studies according to the respective OECD guidelines (acute dermal irritation: OECD guideline 404 and EU method B.4; acute eye irritation: OECD guideline 405 and EU method B.5). The test was performed with rabbits in triplicates and all validity criteria were met.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
The test substance Reaction mass of iso-tridecyl 3-mercaptopropionate and iso-dodecyl 3-mercaptopropionate
produced a primary irritation index of 1.3 and was classified as a slightly ("mild") irritant to rabbit skin according to Draize classification scheme. No corrosive effects were noted. The test material did not meet the criteria for classification as irritant or corrosive according to EU labelling regulations. No symbol and risk phrase are required.Effects on skin irritation/corrosion: slightly irritating
Effects on eye irritation: slightly irritating
Justification for classification or non-classification
The test substance Reaction mass of iso-tridecyl 3-mercaptopropionate and iso-dodecyl 3-mercaptopropionate did not meet the criteria for classification as irritant or corrosive according to EU labelling regulations. No symbol and risk phrase are required.
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