Registration Dossier
Registration Dossier
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EC number: 909-044-3 | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: although data from handbook without details on the method the result can contribute to the evaluation
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Prehled Prumyslove Toxikologie; Organicke Latky
- Author:
- Marhold J
- Year:
- 1 986
- Bibliographic source:
- Avicenum, page 1114
Materials and methods
- Principles of method if other than guideline:
- invivo test with rats (no details)
- GLP compliance:
- not specified
- Test type:
- other: in vivo test with rats
Test material
- Reference substance name:
- Methyl hydrogenphosphonate
- EC Number:
- 237-027-4
- EC Name:
- Methyl hydrogenphosphonate
- Cas Number:
- 13590-71-1
- Molecular formula:
- CH5O3P
- IUPAC Name:
- Phosphonic acid, monomethyl ester
- Test material form:
- other: liquid
- Details on test material:
- no details given
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- no details given
- Doses:
- no details given
- No. of animals per sex per dose:
- no details given
- Control animals:
- not specified
- Details on study design:
- no details given
- Statistics:
- no details given
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 740 mg/kg bw
- Mortality:
- no details given
- Clinical signs:
- other: no details given
- Gross pathology:
- no details given
Applicant's summary and conclusion
- Executive summary:
Marhold (1986) reported LD50(rat, oral) = 1740 mg/kg bw, details were not given.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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