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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other: extracted from ECHA database
Title:
Unnamed
Year:
1991

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine
EC Number:
406-030-4
EC Name:
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine
Cas Number:
105812-81-5
Molecular formula:
C13H18FNO
IUPAC Name:
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine

Test solutions

Vehicle:
yes
Details on test solutions:
Direct dispersion in water with the aid of shielded propeller-stirrers.

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Test type:
static
Water media type:
not specified
Limit test:
no
Total exposure duration:
96 h

Test conditions

Hardness:
50 mg CaCO3

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
45 mg/L
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
42 mg/L
Basis for effect:
mortality (fish)
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
38 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
38 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
18 mg/L
Basis for effect:
mortality (fish)

Applicant's summary and conclusion