Registration Dossier

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
31st August 1995
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Comparable to guideline study with acceptable restrictions. This study was performed in compliance with the GLP regulations. Only memorandum available; no full study report.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1995
Report Date:
1995

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
Deviations:
not specified
Principles of method if other than guideline:
No further details were provided.
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
No further details were provided.
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
No further details were provided.

Sampling and analysis

Analytical monitoring:
not specified
Details on sampling:
No further details were provided.

Test solutions

Vehicle:
not specified
Details on test solutions:
No further details were provided.

Test organisms

Test organisms (species):
activated sludge
Details on inoculum:
No further details were provided.

Study design

Test type:
not specified
Water media type:
not specified
Remarks on exposure duration:
No further details were provided.
Post exposure observation period:
No further details were provided.

Test conditions

Hardness:
No further details were provided.
Test temperature:
No further details were provided.
pH:
No further details were provided.
Dissolved oxygen:
No further details were provided.
Salinity:
No further details were provided.
Nominal and measured concentrations:
No further details were provided.
Details on test conditions:
No further details were provided.
Reference substance (positive control):
not specified

Results and discussion

Details on results:
No significant inhibition in respiration rate of the sludge (> 10 %) was recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre.
Results with reference substance (positive control):
No further details were provided.
Reported statistics and error estimates:
No further details were provided.

Any other information on results incl. tables

No further details were provided.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
No significant inhibition in respiration rate of the sludge (> 10 %) was recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre. Thus under the conditions of the test PTH-decahydroamide (Ro 31-9373/ 000) was not toxic to waste water bacteria.
Executive summary:

The study procedure described was performed on the basis of EC directive 87/302/EEC, Part C (adopted 1988) and OECD guideline No. 209 (1984). No significant inhibition in respiration rate of the sludge (> 10 %) was recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre. Thus under the conditions of the test PTH-decahydroamide (Ro 31-9373/ 000) was not toxic to waste water bacteria.