Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: well performed OECD study but without GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.31
Temp.:
23 °C
pH:
ca. 4.9

Applicant's summary and conclusion

Conclusions:
The Log Pow of the test substance is -0.31 at 23°C.
Executive summary:

The partition coefficient n-octanol/water was determiend according to OECD 107 with the shake flask method. 10, 20 and 40 ml of a stock solution in water saturated n-octanol was shaken with 20 ml water (in duplicate) at 23 °C and the concentration of the test substance was determiend by UV-vis-spectroscopy.