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EC number: 601-409-2 | CAS number: 116020-44-1
For eleven common liquid crystalline structures a category of typical compounds was established sharing chemical structural aspects, physicochemical properties and biological responses in assays for aquatic toxicity.
The query compound fulfils the category criteria for the chemical applicability domain, the physiochemical space and the biological response in the aquatic toxicity assays.
In short term test in Daphnia and in long term tests in fish the query compound shows NOECs above the water solubility limit.
Based on these data the category provides sufficient and reliable information to fill the data gap for the long term toxicity testing on invertebrates, i.e. Daphnia Magna Reproduction Test.
In conclusion, there is sufficient and reliable evidence from the chemical category and for the query compound itself to conclude that the test material is not toxic to aquatic species in acute and in long term settings up the limit of water solubility. Therefore the data requirement according to REACH Annex IX, 9.1.5 is fulfilled and no further experimental testing is considered justified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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