3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid

Guidance on Safe Use

First-aid measures

Inhalation: Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation.Get medical attention if adverse health effects persist or are severe . If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway.

Loosen tight clothing such as a collar, tie, belt or waistband.

Ingestion: Wash out mouth with water. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention if adverse health effects persist or are severe. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Skin contact

Wash skin immediately with plenty of water and soap. Remove contaminated clothing and shoes. Continue to rinse for at least 10 minutes. Get medical attention.  Wash clothing before reuse. Clean shoes thoroughly before reuse.

Eye contact

Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses.

Continue to rinse for at least 10 minutes. Get medical attention.

Fire-fighting measures

Suitable extinguishing media:  In case of fire, use water spray (fog), foam, dry chemical or CO2.

Unsuitable extinguishing media: None known

Special exposure hazards: No specific fire or explosion hazard. Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. In case of fire and/or explosion do not breathe fumes. Keep containers cool by spraying with water is exposed to fire. Collect contanminated extinguishing water seperately, do not allow to reach sewage or effluent systems. Dispose of in accordance with official regulations.

Hazardous combustion products: No specific data

Special protective equipment for fire-fighters

Fire-fighters should wear appropriate protective equipment and selfcontained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Accidental release measures

Personal precautions : No action shall be taken involving any personal risk or without suitable training. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilt material. Provide adequate ventilation. Put on appropriate personal protective

equipment.

Environmental precautions

Avoid dispersal of spilt material and runoff and contact with soil, waterways, drains and sewers. I

Large spill :

Move containers from spill area. Prevent entry into sewers, water courses, basements or confined areas. Vacuum or sweep up

material and place in a designated, labelled waste container.

Dispose of via a licensed waste disposal contractor.

Small spill :

Move containers from spill area. Vacuum or sweep up material and place in a designated, labelled waste container. Dispose of via a

licensed waste disposal contractor.

Handling and storage

Manufacture and use of this chemical intermediate takes place under strictly controlled conditions, as described in Art. 17/18 REACH. The substance is rigorously contained during manufacturing and use and appropriate risk management measures including PPE (i.g. during charging or sampling) are applied. Occupational exposure is reduced to a minimum and well controlled by measurements. A management system covering all general aspects of a chemical production is in place, especially cleaning and maintenance of plants and equipment. An authorisation scheme based on instructions covering the whole process ensures that only trained and authorised staff handles the substance.

Handling: Put on appropriate personal protective equipment. Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not

ingest.  Avoid contact with eyes,  skin or clothing.  Avoid release to the environment. Keep in the original container or an approved alternative made from a

compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous.

Storage:

Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials and food and drink. Keep container tightly closed and sealed until ready for use. Containers

that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabelled containers. Use

appropriate containment to avoid environmental contamination.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

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Shipping information

Proper shipping name and description:

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Chemical name:

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Labels:

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Special provisions / remarks

Special provisions:

Not regulated

Remarks:

Not dangerous cargo. Keep dry. Keep away from foodstuffs, acids and alkalis.

Inland waterway transport (UN RTDG/ADN(R))

UN number:

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Shipping

Labels:

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Special provisions / remarks

Remarks:

Special precautions for user/Additional info: Not regulated.
Not dangerous cargo. Keep dry. Keep away from foodstuffs, acids and alkalis.

Marine transport (UN RTDG/IMDG)

UN number:

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Shipping information

Proper shipping name and description:

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Chemical name:

--

Labels:

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Special provisions / remarks

Remarks:

Special precautions for user/Additional info: Not regulated.
Not dangerous cargo. IKeep dry. Keep away from foodstuffs, acids and alkalis.

Air transport (UN RTDG/ICAO/IATA)

UN number:

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Shipping information

Proper shipping name and description:

--

Chemical name:

--

Labels:

--

Special provisions / remarks

Remarks:

Special precautions for user/Additional info: Not regulated.
Not dangerous cargo. Keep dry. Keep away from foodstuffs, acids and alkalis.

Additional transport information

Additional information

Special provisions / remarks / other:

The producer uses packaging for the product, which meets the requirements for products with a hazard potential as far as
tightness and stability are concerned. Consequently transport is possible without increased danger as long as attention is paid to the usual
measures such as stack height, protection against falling and correct labelling. In case of partially fractured containers, these must be kept closed carefully on any transport, in order to prevent spillage.

Exposure controls / personal protection

Exposure limit values: Not available

Recommended monitoring procedures:

If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to

determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective

equipment. Reference should be made to European Standard EN 689 for methods for the assessment of exposure by inhalation to

chemical agents and national guidance documents for methods for the determination of hazardous substances.

Risk management measures/Occupational exposure controls

Technical measures: If this product contains ingredients with exposure limits, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure below any recommended or statutory limits. The substance shall be rigorously contained by technical means during its whole lifecycle including manufacture, pruification, cleaning and maintenance of equipment, sampling, analysis, loading and unloading of equipment or vessels, waste disposal or prufication and storage. Procedural and control technologies shall be used that minimise emission and any resulting exposure. In cases of accident and where waste is generated, procedural and/or control technologies shall be used to minimise emissions and the resulting exposure during purification or cleaning and maintenance. Only properly trained and authorised personnel shall handle the substance. In case of cleaning and maintenance works, special procedures such as purging ans washing shall be applied before the system is opened and entered. Product-handling procedures shall be well documented.

Personal protection measures:

Respiratory protection: Use a properly fitted, air-purifying or air-fed respirator complying with

an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or

anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator.

Recommended: In case of dust formation particle filter

Hand protection: Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical

products if a risk assessment indicates this is necessary. After contamination with product change the gloves immediately and

dispose of them according to relevant national and local regulations.

<1 hours (breakthrough time): Butyl rubber - IIR, Fluorinated rubber - FKM or Polyvinyl chloride - PVC

Eye protection: Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid

exposure to liquid splashes, mists, gases or dusts.

Recommended: Safety glasses with side-shields

Skin protection: Personal protective equipment for the body should be selected based on the task being performed and the risks involved and

should be approved by a specialist before handling this product.

Recommended: Wear protective clothing.

Hygiene measures: Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory

and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated

clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

Environmental exposure controls: Emissions from ventilation or work process equipment should be checked to ensure they comply with the

requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

Stability and reactivity

Stability: The product is stable

Possibility of hazardous reactions: Under normal conditions of storage and use, hazardous reactions will not occur.

Conditions to avoid: Keep away from alkalis.

Hazardous decomposition products: Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Disposal considerations

Product

Methods of disposal: Examine possibilities for re-utilisation. Product residues and uncleaned empty containers should be packaged, sealed,

labelled, and disposed of or recycled according to relevant national and local regulations. Where large quantities are concerned, consult the

supplier. When uncleaned empty containers are passed on, the recipient must be warned of any possible hazard that may be caused by residues.

For disposal within the EC, the appropriate code according to the European Waste List (EWL) should be used.

It is among the tasks of the polluter to assign the waste to waste codes specific to industrial sectors and processes according to the European

Waste List (EWL).

Hazardous waste: The classification of the product may meet the criteria for a hazardous waste.

Packaging

Methods of disposal: The generation of waste should be avoided or minimised wherever possible. Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible.

Special precautions: This material and its container must be disposed of in a safe way. Care should be taken when handling emptied containers that have not been cleaned or rinsed out. Empty containers or liners may retain some product residues. Avoid dispersal of spilt material and runoff and contact

 with soil, waterways, drains and sewers.