Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
skin sensitisation
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

Skin Sens 1, H317: May cause an allergic skin reaction.

Migrated from Short description of key information:
read across from data/evidence based expert jugement:
THPC is considered a skin sensitiser based on two other existing data: a 20% THPC aqueous solution was found positive for skin sensitisation and a 75% THPS aqueous solution was found positive for skin sensitisation both by means of the GPMT (Magusson&Kligman)

Respiratory sensitisation

Endpoint conclusion
Additional information:
Migrated from Short description of key information:
The repiratory sensitisation potential has not been tested.
Technical THPC (80%) is an liquid solution. THPC is ionic compound which cannot be inhaled other than by means of an aerosol. Under intended conditions of use the formation of an aerosol is not a realistic exposure scenario for men.

Justification for classification or non-classification

Skin Sensitisation: data conclusive for classification (Skin Sens. Cat 1; H317).

Respiratory Sensistisation: test waived (no exposure); no classification required.