Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Justification for selection of genetic toxicity endpoint
Data are of K1 quality and conducted in compliance with GLP.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

The mutagenic potential has been assessed by exposure to S. typhimurium TA 1535, TA 1537, TA 98 and TA 100 and E. coli WP2 uvr A in DMSO with and without S9 metabolic activations in accordance with the OECD 471 test guideline in compliance with GLP. Under the conditions of the test, the test substance was shown to have no mutagenic activity to bacterium tester strains.

The clastogenic potential has been assessed by exposure to cultured human lymphocytes in DMSO with and without S9 metabolic activations in accordance with the OECD 473 test guideline in compliance with GLP. Under the conditions of the test, the test substance was shown to have no mutagenic clastogenic in the presence and absence of metabolic activation.