Registration Dossier

Administrative data

Endpoint:
short-term repeated dose toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Available data in the IUCLID Chemical Data Sheet; the data have not undergone any evaluation by the European Commission. The method is not known.

Data source

Reference
Reference Type:
grey literature
Title:
Unnamed
Year:
2000
Report Date:
2000

Materials and methods

Principles of method if other than guideline:
Method not available
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
not specified

Administration / exposure

Route of administration:
oral: gavage
Duration of treatment / exposure:
14 days
Frequency of treatment:
daily
Doses / concentrations
Remarks:
Doses / Concentrations:
7.5, 15, 30, 60, 120 mg/kg bw
Basis:

Control animals:
yes

Results and discussion

Effect levels

Dose descriptor:
NOAEL
Effect level:
> 120 mg/kg bw/day (nominal)
Based on:
not specified
Sex:
not specified

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion