Registration Dossier

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1990

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
FAT 92274/A

Test animals

Species:
rabbit
Strain:
New Zealand White

Results and discussion

Any other information on results incl. tables

Under the experimental conditions employed substance induced erythema reactions when applied to the clipped albino rabbit skin.

The mean values of the recordings 24 to 72 hours after application are below the threshold of significance (2 score for erythema

or edema)

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
According to the EEC classification of the results obtained 24 to 72 hours after removing the bandages, the substance can be classified as
non-irritant in albino rabbits. The skin reactions observed were reversible until the end of the observation period on day 3.
Executive summary:

non-irritant in albino rabbits