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EC number: 696-318-8 | CAS number: 174489-43-1
Table 1: Individual Eye Irritation Scores
SEX / ANIMAL NO.
F / 813
F / 836
AFTER 1 HOUR
AFTER 24 HOURS
AFTER 48 HOURS
AFTER 72 HOURS
CE: CONTROL EYE TE: TEST EYE
Table 2: Summary Eye Irritation Indices (OECD/EEC)
Mean Scores for 24, 48 and 72 hour readings
Table 3: Body Weights (g)
AT TEST START
AT TEST END (3 DAYS)
An eye irritation/corrosion test was conducted with test article CA 2219 A (Intermediate of CGA 276854) (batch 249-GE001/SU). The test article (0.1 ml) was instilled into the conjunctival sac of one eye of three rabbits; the second eye served as a control. The test eyes were gently washed with distilled water 24 hours after treatment. Eyes were examined for irritation at 1, 24, 48 and 72 hours after treatment.
Redness of the conjunctiva was observed in all animals at the 1-hour reading. All eye reactions were clear by day 1. There was no mortality. No remarkable clinical observations were recorded. Body weights were not affected by treatment.
According to the test results, CA 2219 A (Intermediate of CGA 276854) is not required to be classified for eye irritation according to Commission Directive 93/21/EEC, issued May 4, 1993.
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