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Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Handbook data. No detailed procedure. Route is intravenous injection not by oral, which seriously impacts the applicability of the study.

Data source

Reference
Reference Type:
review article or handbook
Title:
The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition
Author:
O'Neil, M.J.
Year:
1968
Bibliographic source:
Whitehouse Station, NJ: Merck and Co., Inc., 1968., p. 961

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
no data
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium iodide
EC Number:
231-679-3
EC Name:
Sodium iodide
Cas Number:
7681-82-5
Molecular formula:
INa
IUPAC Name:
sodium iodide
Details on test material:
no data

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
285 mg/kg bw
Based on:
not specified

Any other information on results incl. tables

no data

Applicant's summary and conclusion

Conclusions:
The LD50 iv to rat is 285 mg/kg bw