Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Handbook data. No detailed procedure. Route is intravenous injection not by oral, which seriously impacts the applicability of the study.

Data source

Reference
Reference Type:
review article or handbook
Title:
The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition
Author:
O'Neil, M.J.
Year:
1968
Bibliographic source:
Whitehouse Station, NJ: Merck and Co., Inc., 1968., p. 961

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
no data
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium iodide
EC Number:
231-679-3
EC Name:
Sodium iodide
Cas Number:
7681-82-5
Molecular formula:
INa
IUPAC Name:
sodium iodide
Details on test material:
no data

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
285 mg/kg bw
Based on:
not specified

Any other information on results incl. tables

no data

Applicant's summary and conclusion

Conclusions:
The LD50 iv to rat is 285 mg/kg bw