Registration Dossier
Registration Dossier
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EC number: 202-608-3 | CAS number: 97-78-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h) = 29.7 mg/L for Daphnia magna (OECD 202) (read-across)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 29.7 mg/L
Additional information
No studies for the short-term toxicity of N-lauroylsarcosine (CAS 97-78-9) to aquatic invertebrates are available. Therefore data from the corresponding salt, Sodium N-lauroysarcosinate (CAS 137-16-6), are used as read across.
This read across approach is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach as is explained within the analogue justification in section 13. Since dissociation of the sodium salt under environmental conditions yields the same ionic species as dissociation of the acidic form of the substance, this read across can be considered as justified.
The short-term toxicity of the read-across substance Sodium N-lauroylsarcosinate (CAS 137-16-6) to aquatic invertebrates was investigated in one study with Daphnia magna according to OECD guideline 202 and GLP (Krain, 2004). The study did not include analytical verification of the test substance concentrations. Five concentrations up to nominal 500 mg/L were tested in the study. The EC50 (48 h) was determined to be 29.7 mg/L (nominal).
Based on the available result from one structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which is characterized by a comparable structure, it can be concluded that N-lauroylsarcosine (CAS 97-78-9)will show a similar toxicity to aquatic invertebrates.
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