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EC number: 203-161-7 | CAS number: 103-95-7
Three studies on the acute aquatic toxicity of the substance are available with the following findings: Freshwater fish: LC50 = 1.092 mg/L; Freshwater invertebrates: EC50 = 1.4mg/L; Freshwater algae: EC50 = 3.8 mg/L.
Chronic aquatic toxicity data is only available for algae; the 96-hour NOEC is 0.70 mg/L (based on growth rate). No marine species were tested. No tests on toxicity to sediment-dwelling organisms or soil organisms are available.
The PNEC for the aquatic environment are derived from the lowest effect level observed in the available acute aquatic toxicity tests by applying the following assessment factors to the lowest L(E)C50 of 1.092 mg/L: PNEC aqua (freshwater): 1000; PNEC aqua (marine water): 10000; PNEC aqua (intermittent): 100.
PNEC STP is derived from the available study on microbial respiration inhibition study giving a EC50 (over 3 hours) of 100mg/L by applying an assessment factor of 100.
PNECs for sediment and soil are calculated from the aquatic PNECs with the equilibrium partitioning method according to ECHA guidance R.10.
PNEC sediment (freshwater/marine water): Wet weight PNECs are calculated with Ksusp-water = 28.95 m3/m3, density of suspended particles = 1150 kg/m3 (wet weight); conversion to dry weight is done with factor of 4.6. (PNEC sediment freshwater = 2.75E-2 mg/kg wet weight; PNEC sediment marine water = 2.75E-3 mg/kg wet weight).
PNEC soil: Wet weight PNECs are calculated with Ksoil-water = 34.06 m3/m3, density of soil = 1700 kg/m3 (wet weight); conversion to dry weight is done with factor of 1.13 (PNEC soil = 0.0219 mg/kg wet weight)
PNEC secondary poisoning was derived from the available information on repeated dose toxicity 300 mg/kg bw converting to PNECoral by i) by multiplying by a factor of 33.3 (Oryctolagus cuniculus, rabbit) to convert to a concentration (NOEC) and ii) dividing by an assessment factor of 300 (<28 day study) in accordance with ECHA R.10.8.
Environmental classification and labelling of a substance is generally based on data from short-term aquatic toxicity results, the ready biodegradability of the substance and the measured octanol/water partition coefficient. Available adequate chronic toxicity data is also relevant for the assessment of long-term aquatic hazards (Regulation 286/2011/EC).
Short-term aquatic toxicity data is available for all three trophic levels. The lowest short-term L(E)C50 was for fish with a 96-hour LC50 value of 1.09 mg/l. Chronic aquatic toxicity data is only available for algae; the 96-hour NOEC is 0.70 mg/L (based on growth rate). Cyclamen aldehyde is readily biodegradable and has a log Kow of 3.4.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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