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Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
other: human case
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
other: not rated
Rationale for reliability incl. deficiencies:
other: Since the test substance is selenium dioxide, the reference is not relevant for evaluation of eye irritation for selenous acid.

Data source

Reference
Reference Type:
publication
Title:
Selenium burn of the eye. Review of a case with review of the literature.
Author:
Middleton JM
Year:
1947
Bibliographic source:
Arch. Ophthalmol. 38, 806-811

Materials and methods

Study type:
poisoning incident
Endpoint addressed:
eye irritation
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
A chemist was accidently sprayed with selenium dioxide at Dec. 13, 1944, sustaining burns of both eyes, the entire face and the back of the neck. He irrigated the parts immediately with tap water and presented himself for treatment in Hospital.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Selenium dioxide
EC Number:
231-194-7
EC Name:
Selenium dioxide
Cas Number:
7446-08-4
Molecular formula:
O2Se
IUPAC Name:
oxoselane oxide
Details on test material:
- Name of test material (as cited in study report): selenium dioxide

Method

Subjects:
A chemist was accidently sprayed with selenium dioxide at Dec. 13, 1944, sustaining burns of both eyes, the entire face and the back of the neck. He irrigated the parts immediately with tap water and presented himself for treatment in Hospital.

Results and discussion

Results of examinations:
Since the test substance is selenium dioxide, the reference is not relevant for evaluation of eye irritation for selenous acid.

Applicant's summary and conclusion

Conclusions:
Since the test substance is selenium dioxide, the reference is not relevant for evaluation of eye irritation for selenous acid.

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