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EC number: 485-320-2 | CAS number: 221667-31-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The ecotoxicological profile of the substance has been well defined. Short term and long term tests with species of three different trophic levels are available for the substance (fish, invertebrates, algae and aquatic plants).
Acute toxicity tests (96 h) on freshwater and marine fish species (bluegill sunfish, rainbow trout and sheepshead minnow) resulted in no effects up to the highest tested concentration. The LC50 (96 h) for short-term tests with freshwater fish is therefore ≥101 mg a.i./L (arith. mean measured). For the saltwater species sheepshead minnow a LC50 (96 h) of ≥106 mg a.i./L (arith. mean measured) was determined. A chronic test on fathead minnow (early life stage study over 35 days) resulted in a NOEC of 4.67 mg/L (arith. mean measured) based on growth (length and weight).
Acute toxicity tests on freshwater invertebrates (Daphnia magna), resulted in an EC50 of > 100 mg a.i./L (nominal) and no toxic effects were observed during the study. The EC50 for marine invertebrates were >100 mg a.i./L (arith. mean measured) for Americamysis bahia and >94 mg a.i./L (arith. mean measured) for Crassostrea virginica.
The 21-day exposure of daphnia to the test substance resulted in a NOEC of 57.2 mg a.i./L and a LOEC of 111.6 mg a.i./L based on reproduction and growth.
For freshwater algae (Pseudokirchneriella subcapitata), no toxic effects occurred up to the highest tested concentration of 100 mg a.i./L (nominal). The 72h EC50 (growth rate) was therefore >99.7 mg/L (arith. mean measured) and the NOEC (growth rate) ≥99.7 mg/L (arith. mean measured).
Additionally a higher tiered test was performed in order to determine the potential toxicity of the substance to Lemna gibba. The determined NOEC (7 d) was 51.1 mg a.i./L for frond number, biomass and growth rate for frond counts, respectively. The EC50 (7 d) for all endpoints measured was >104 mg a.i./L which was the highest concentration tested. Fronds in all levels appeared normal as compared to the control.
The effects of the substance on the respiration of microorganisms (activated sludge) was examined in a study according to OECD 209. No effects >25% on nitrogen or carbon transformation, compared to the controls, was observed.Therefore, inhibition of the degradation activity of activated sludge is not anticipated.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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