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EC number: 411-950-4 | CAS number: 96562-58-2 DHPPME; MAK-ME; MEHPOPS; R-MAQ-ME
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Under the conditions of this study, the test material was found to be not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
A study was conducted to evaluate the ready biodegradability of the test material in accordance with the standardised guidelines OECD 301B and EU Method C.5 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
The test material was added to a chemically defined liquid medium, inoculated with sewage micro-organisms and aerated at room temperature at concentrations of 8.5 and 17.9 mg DOC/L. CO2 released was trapped as BaCO3 and degradation was followed by CO2 analysis over a 36 day period as a plateau was not reached after 28 days. After reference to suitable blank controls, the total amount of CO2 produced by the test material was determined for the test period and calculated as a percentage of the total CO2 that the test material, based on its carbon content, could have theoretically produced. The procedure was checked by means of an inoculum control substance and an inhibition/toxicity control.
The total endogenous CO2 produced from the inoculum blank was 9.4 and 27.2 mg/L after 28 and 36 days, respectively. The biodegradation expressed as a percentage of the actual and theoretical potential quantities of CO2 evolved was 58 and 30 % after 28 days for the 8.5 and 17.9 mg DOC/L concentrations, respectively. The values obtained after 36 days were 58 and 35 % for the 8.5 and 17.9 mg DOC/L concentrations, respectively.
The results of the toxicity control test were compared with the results achieved through addition of the individual values for each material tested in isolation. No significant differences are visible which would indicate that the test material is inhibiting the micro-organisms.
Under the conditions of this study, the test material was found to be not readily biodegradable.
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