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Diss Factsheets
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EC number: 208-645-1 | CAS number: 536-74-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Explosiveness
Administrative data
- Endpoint:
- explosive properties of explosives
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is an organic substance or mixture containing chemical groups associated with explosive properties, but the exothermic decomposition energy is less than 500 J/g and the onset of exothermic decomposition is below 500°C
- Justification for type of information:
- JUSTIFICATION FOR DATA WAIVING
According to REACh Annex VII / column 2, the study does not need to be conducted if the organic substance or a homogenous mixture of organic substances contains chemical groups associated with explosive properties, but the exothermic decomposition energy is less than 500 J/g and the onset of exothermic decomposition is below 500 °C.
Based on criteria from:
- Regulation (EC) N°1272/2008 (CLP) Annex I, §2.1.4.,
- UN Recommendations on the Transport of Dangerous Goods - Manual of Tests and Criteria (7th revised edition, 2019), Appendix 6 Screening procedures §A6.3)
- ECHA endpoint specific guidance on Information Requirements (R.7a, v6.0, July 2017, §R.7.1.11), the exothermic released energy of decomposition is less than 500 J/g, therefore, the explosive properties are not anticipated, and the acceptance procedure for Class 1 explosives shall not apply. No further testing is required.
Cross-reference
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Endpoint:
- thermal stability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08-14 March 2022
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- The study was conducted according to an internationally recognised method, and under GLP. No deviation affected the quality of the study. The substance is adequately identified. Therefore full validation applies.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 113 (Screening Test for Thermal Stability and Stability in Air)
- Version / remarks:
- 1981
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- GLP-BESCHEININGUNG Statement of GLP Compliance (inspected on 28-29 Avril 2021, signed on 21 June 2021)
- Test substance thermally stable:
- ambiguous
- Remarks:
- exothermic event at 56.07°C [assuming decomposition]
- Key result
- Operating temp.:
- >= 0 - <= 520 °C
- Remarks on result:
- other: An unique exothermic event was observed at 56.07 °C (onset)
- Sublimation:
- not determined
- Transformation products:
- not specified
- Test substance stable to sunlight:
- not determined
- Test substance stable to metals / metal ions:
- not determined
- Conclusions:
- The released energy at 56.07°C (onset) was determined to be 142.79 J/g.
- Executive summary:
The thermal profile of the test substance between 0°C and 520°C was determined during a GLP study according to the OECD giuidelmine, using a DSC method.
During the DSC run an exothermic event was observed at an onset of 56.07 °C and this was integrated to derive the related energy (in J/g). The related energy of the observed exothermic event was 142.79 J/g.
Results
Table 1 - Values DSC Indium (Calibration)
Expected Melting point | Measured Melting point | Expected Energy | Measured Energy | Assessment |
156.6 ± 1.0°C | 156.41 °C | 28.45 ± 1.0 J/g | 28.41 J/g | OK |
Table 2 - DSC Screening of the Test Item
Temperature [°C] | Energy [J/g] | |
Exothermal event | 56.07 (Onset) | -142.79 (the minus symbol is stated for the energy of exothermic event) |
The crucible was visually unchanged after the test.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.