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Physical & Chemical properties

Boiling point

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boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
03-25 April 2006
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
The study was conducted according to an internationally recognised method, and under GLP. However, some critical experimental details are missing.
according to guideline
EU Method A.2 (Boiling Temperature)
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. QA statement)
signed 24 February 2006
Type of method:
differential scanning calorimetry
Key result
Boiling pt.:
251.7 °C
Atm. press.:
ca. 101 325 Pa

Table 4.3/1: Boiling point – results


Test No.

Start temperature

Heating rate

Onset temperature


240 °C

+1 °C/min

252.1 °C


240 °C

+1 °C/min

251.4 °C


240 °C

+1 °C/min

251.6 °C

Mean± S.D.

251.7 ± 0.4 °C

Executive summary:

The boiling point of the test substance was determined under GLP according to EU A.2 guideline, using Differential Scanning Calorimetry (DSC).

Three runs were performed and found consistent, so the mean final temperature was retained.

The boiling temperature of test substance has been determined to be 251.7 ± 0.4 °C.

Description of key information

Measured boiling point = 251.7°C (atmP unspecified but expected ambient)

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
251.7 °C

Additional information

A reliable experimental study, conducted according to a recognized EC method and under GLP, is available. Despite restrictions due to missing experimental details, it is considered as a key study, and the result is retained as key data.