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EC number: 690-995-3 | CAS number: 756-12-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
CAS# 756-12-7 is a fluorinated ketone. Direct photolysis is expected to be the dominant atmospheric removal process. CAS# 756-12-7 has a measured atmospheric lifetime of 16 days by this mechanism. It has a boiling point of 26.9 °C at 101.325 kPa. During routine use, most releases are expected to be to the atmosphere. There is no anticipated release to water or wastewater in the EU. Its water solubility cannot be measured owing to its extremely short hydrolytic half life. It hydrolyzes readily in water with a half life much less than 11.5 minutes. However, based upon its intended uses this compound will remain in the atmosphere when released from industrial applications.
CAS# 756-12-7 has an estimated n-octanol:water partition coefficient (log P) of 1.82, and is expected to have no bioaccumulation potential. The actual log P value cannot be measured due to rapid hydrolysis. The high volatility mitigates against exposure of aquatic organisms, and bioaccumulation is unlikely to be a concern even if log P were >4.5. Rapid hydrolysis would further reduce exposure in aquatic systems.
CAS# 756-12-7 is not biodegradable (0% oxygen consumption in an OECD 301 D closed bottle test). Due to rapid hydrolytic activity, the parent compound will not be present as such in aquatic systems even if brought into contact with water. The degradation products are a hydrated ketone (geminal diol) which is formed rapidly, followed by scission to form trifluoroacetic acid and a volatile hydrofluorocarbon. As suggested by the ready biodegradation test result, the ultimate hydrolysis products are also not biodegradable. In summary, the environmental fate is expected to be dominated by direct photolysis in the atmosphere.
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