Registration Dossier
Registration Dossier
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EC number: 856-564-0 | CAS number: 1355357-49-1
Guidance on Safe Use
Administrative data
First-aid measures
Description of first aid measures
IF exposed or concerned: Get medical advice/attention. The first responders must always wear appropriate personal protective equipment (see SECTION 8.2).
Most important symptoms and effects, both acute and delayed
The substance has not been fully investigated from a toxicological point of view.
Indication of any immediate medical attention and special treatment needed
Basic first aid and symptomatic treatment. Symptoms of poisoning may occur even at a later stage after the exposure; therefore, medical surveillance is recommended for 48 hours after the accident.
Fire-fighting measures
Extinguishing media
Use extinguishing media appropriate to the source of the fire and the surrounding area.
Special hazards arising from the substance or mixture
The substance is not flammable.
Advice for firefighters
Evacuate and isolate the area until complete fire extinction, by limiting access only to trained personnel. Firefighters must always wear appropriate protective equipment: positive pressure self-contained breathing apparatus; fireproof clothing; fireproof gloves; firefighter’s boots. Ensure adequate ventilation. Avoid breathing gases/vapours. Avoid contact with eyes, skin and clothing. Stay upwind. Remove containers if it can be done without risk. Prevent the contaminated extinguishing water flowing into drains or waterways.
Accidental release measures
Personal precautions, protective equipment, and procedures in case of emergency
Alert the emergency personnel. Evacuate and isolate the area until complete dispersion of the substance and restrict the access only to trained personnel. Ensure adequate ventilation. Avoid breathing dust/mist/vapours. Avoid contact with eyes and skin. Wear appropriate personal protective equipment (see SECTION 8.2).
Environmental precautions
Prevent the substance from leaking into the environment and run off into drains, surface waters and groundwater. Alert competent authorities if large amounts into drains or watercourses.
Methods and material for containment and cleaning up
Transfer in a properly labeled container. Dispose of in accordance with local and national legislation. Clean surface thoroughly in order to remove residual contamination.
Reference to other sections
See SECTION 8.2 and SECTION 13.1.
Handling and storage
This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18 for transported isolated intermediates. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at the manufacturing site.
Precautions for safe handling
The work place and work methods shall be organized in such a way that direct contact with the substance is prevented or minimized. Ensure adequate ventilation. Avoid breathing dust/mist/vapours. Avoid contact with eyes and skin. Wear appropriate personal protective equipment (see SECTION 8.2). Do not eat, drink, or smoke during use. Wash hands and other exposed areas after use. Wash periodically clothes and personal protective equipment to remove contaminants. Handle in accordance with good industrial hygiene and safety practices.
Conditions for safe storage, including any incompatibilities
Store in a cool, dry and well ventilated place. Avoid exposure to moisture and direct sunlight. Store away from heat/sparks/open flames. Avoid the accumulation of static discharges. Store away from incompatible materials (see SECTION 10.5).
Specific end use(s)
Pharmaceutical intermediate.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- Not applicable
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Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- Not applicable
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Marine transport (UN RTDG/IMDG)
- UN number:
- Not applicable
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- Not applicable
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Exposure controls / personal protection
This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18 for trasnported isolated intermediates. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at the manufacturing site.
Control parameters
The substance has no occupational exposure limit values.
Exposure controls
Wear personal protective equipment in accordance with standards set by European and national legislation. Consult the supplier in all cases before making a final decision.
Skin protection: Wear protective clothing with long sleeve.
Hand protection: Wear work gloves impervious to chemicals made of nitrile rubber.
Eye protection: Wear appropriate safety glasses with side shields.
Respiratory protection: In the case of potential exposure, wear a respirator with an approved filter.
Technical and hygienic measures: Provide local exhaust ventilation suction or other devices to maintain the levels of particles in the air below the recommended exposure limits. Equip the plant with exhaust hoods or equivalent dust collection devices. Equip with emergency showers and eyewash device the areas in which handling and storage of the product takes place. Do not eat, drink, or smoke during use. Wash hands and other exposed areas after use. Wash periodically clothes and personal protective equipment to remove contaminants. Handle in accordance with good industrial hygiene and safety practices.
Stability and reactivity
Reactivity: The substance is not reactive under recommended conditions of use.
Chemical stability: The substance is stable under recommended conditions of use and storage.
Possibility of hazardous reactions: The possibility of hazardous reactions is not expected under recommended conditions of use and storage.
Conditions to avoid: Avoid exposure to moisture and direct sunlight. Keep away from heat/sparks/open flames.
Incompatible materials: Not known.
Hazardous decomposition products: Not expected.
Disposal considerations
This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18 for transported isolated intermediates. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at the manufacturing site.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
