4-Ethyl-2’-fluoro-4’-bromobiphenyl

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2019-03-05

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

31.8 °C

Atm. press.:

1 013.25 hPa

Decomposition:

no

Sublimation:

no

Melting point / melting range: DSC measurement

Three DSC measurements with a heating rate of 10 K/min showed an endothermal effect (melting) in the temperature range of 30 - 45 °C. The onset temperature (see Table 1) was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline.

 

Table 1: Melting point (DSC measurements)

Test item/ mg	Starting temperature / °C	Final test temperature / °C	Temperature range (endo- thermal) / °C	Onset (melting) / °C	Crucible	Observations after the measurement
12.31	25	500	30-45	32.04	Aluminium with a hole	Empty crucible, mass loss: 100 %
15.13	0	100	30-45	31.64	Aluminium with a hole	Test item was a clear melt, no mass loss
16.09	25	400	30-45	31.80	Aluminium with a hole	Empty crucible, mass loss: 100 %

 

The test item had a melting point of 31.8 °C.

Conclusions:

The melting point of the test item was determined to be 31.8 °C.

Executive summary:

A study was conducted according to OECD TG 102 and Regulation (EC) No 440/2008 method A.1 to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 12-16 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. Three DSC-measurements in aluminium crucibles with a hole showed an endothermic effect in the temperature range of 30 - 45 ° with an onset temperature of 31.6 °C to 32.0 °C. The onset temperatures are derived from the intersection of the tangent line with the highest slope of the endothermic peak with the baseline. The maximum test temperature was 500 °C and the test item appeared melted after the tests. Based on the results of the DSC-measurements it was concluded that the test item has a melting point of 31.8 °C.

Description of key information

The melting point of the test item was determined to be 31.8 °C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

31.8 °C

Additional information

A study was conducted according to OECD TG 102 and Regulation (EC) No 440/2008 method A.1 to determine the melting point of the test item using differential scanning calorimetry (refrence 4.2 -1). The test item was weighed into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 12-16 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. Three DSC-measurements in aluminium crucibles with a hole showed an endothermic effect in the temperature range of 30 - 45 ° with an onset temperature of 31.6 °C to 32.0 °C. The onset temperatures are derived from the intersection of the tangent line with the highest slope of the endothermic peak with the baseline. The maximum test temperature was 500 °C and the test item appeared melted after the tests. Based on the results of the DSC-measurements it was concluded that the test item has a melting point of 31.8 °C.