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Administrative data

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07 Jan 2019 - 14 Feb 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2012
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
Version / remarks:
2002
Deviations:
no
GLP compliance:
yes
Type of method:
air comparison pycnometer (for solids)

Test material

Constituent 1
Chemical structure
Reference substance name:
(S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide
Cas Number:
357338-13-7
Molecular formula:
C11H18N2O2
IUPAC Name:
(S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide
Test material form:
solid: particulate/powder
Details on test material:
- Appearance: Off-white powder
- Storage condition of test material: In refrigerator protected from light
Specific details on test material used for the study:
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
The test item was dried for 44 hours in a desiccator under vacuum using silica gel as the drying agent at 18.7 ± 0.1°C and protected from light.

Results and discussion

Densityopen allclose all
Key result
Type:
relative density
Density:
1.1 other: dimensionless
Temp.:
20 °C
Remarks on result:
other: D 20 /4
Key result
Type:
density
Density:
1.1 g/cm³
Temp.:
20 °C

Any other information on results incl. tables

Relative density:

Experiment 1: 1.102

Experiment 2: 1.104

Mean: 1.10

Applicant's summary and conclusion

Conclusions:
The relative density D20/4 of the substance was determined to be 1.10.
Executive summary:

The relative density of the substance was determined in a GLP study according to EC A.3, OECD 109 and OPPTS 830.7300 (method: air comparison pycnometer (for solids)).

A gas comparison pycnometer was used with Helium as the gas. The relative density D20/4 was determined in duplicate obtaining a mean value of 1.10.