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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
01-2019
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Justification for type of information:
1. SOFTWARE
- EPI suite

2. MODEL (incl. version number)
v4.11

3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL
- Oc1ccc(O)cc1P2(c(cccc3)c3c(cccc4)c4O2)=O

4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
[Explain how the model fulfils the OECD principles for (Q)SAR model validation. Consider attaching the QMRF or providing a link]
- Defined endpoint:
KOWWIN Program (v1.68)
- Unambiguous algorithm:
LOGKOW FRAGMENT DESCRIPTION
- Defined domain of applicability:
- Appropriate measures of goodness-of-fit and robustness and predictivity:
- Mechanistic interpretation:

Principles of method if other than guideline:
- Principle of test:
QSAR model
Key result
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Remarks on result:
not readily biodegradable based on QSAR/QSPR prediction
Details on results:
Ready biodegradability prediction: NO (Episuite assessed value)
Anaerobic model prediction: Does not degradable fat (Episuite assessed value)

Ready biodegradability prediction: NO (Episuite assessed value)

Anaerobic model prediction: Does not degradable fast (Episuite assessed value)

Interpretation of results:
not readily biodegradable
Conclusions:
Ready biodegradability prediction: NO (Episuite assessed value)
Anaerobic model prediction: Does not degradable fast (Episuite assessed value)

Description of key information

Ready biodegradability prediction: NO (Episuite assessed value)

Anaerobic model prediction: Does not degradable fat (Episuite assessed value)

Key value for chemical safety assessment

Additional information