Reaction mass of Methacryloxypropyl (tris(trialkylsiloxy)silylethyl dimethylsiloxy) silane and oligomers

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: Method for Testing the Biodegradability of Chemical Substances by Microrganisms stipulated in the Testing Methods for New Chemical Substances, Japan

Deviations:

no

Principles of method if other than guideline:

not applicable

GLP compliance:

yes

Specific details on test material used for the study:

Name: HES 10108 (supplied as Dow Corning® BY 16-122 B)
CAS No.: Not Listed
ID No.:HESI0108
Lot No.: 0008624816
Source: Dow Corning Corporation, Auburn, Michigan
Physical Description: Colorless liquid
Purity: 99.3%, used as 100%
Storage Conditions: Room Temperature
Expiration Date: 25 August 2017

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge (adaptation not specified)

Details on inoculum:

Activated sludge cultivated in the laboratory was used. On-site sludge samplimg was carried out at 10 locations (samples from surface water and surface soil of rivers, lakes and inland seas and return sludge from sewage plants). Activated sludge was prepared and maintained under laboratory conditions. For the test,, activated sludge which was cultivated for 18.5 hours after feeding with syntheticsewage was used.

Duration of test (contact time):

28 d

Initial conc.:

100 mg/L

Based on:

test mat.

Parameter followed for biodegradation estimation:

O2 consumption

Details on study design:

Standard test conditions as outlined in the guidelines were used

Reference substance:

aniline

Key result

Parameter:

% degradation (test mat. analysis)

Value:

0

Sampling time:

28 d

Remarks on result:

other:

Remarks:

The test item was not readily biodegradable under the test conditions

Details on results:

The average percentage biodegradation by BOD and that of the test item analytically were 2% and 0%, respectively.

Key result

Parameter:

BOD5

Value:

2 mg O2/g test mat.

Remarks on result:

other:

Remarks:

The test item was not readily biodegradable under the test conditions

Results with reference substance:

The percentage degradation of aniline after 7 days and 14 days were 73% and 85%, respectively.

Validity criteria fulfilled:

yes

Interpretation of results:

under test conditions no biodegradation observed

Conclusions:

Under the conditions of the study, the average percentage biodegradation by BOD and that of the test item analytically were 2% and 0%, respectively. The test item was not readily biodegradable under the test conditions

Executive summary:

The study evaluated the biodegradability of HES 10108 by microorganisms and the study was conducted according to OECD Guidelines 301C and Method for Testing the Biodegradability of Chemical Substances by Microrganisms stipulated in the Testing Methods for New Chemical Substances, Japan and in accordance with the Principles of GLP. The conditions of incubation were-

Concentration of test item - 100 mg/l

Concentration of activated sludge - 30 mg/l (as concentration of suspended solids)

Volume of test solution - 300 ml

Incubation temperature - 25 ± 1 °C

Incubation duration - 28 days (under dark condition)

Biodegradation was measured by estimating the BOD and analytically by measuring the concentration of the test item using validated HPLC methods.

Under the conditions of the study, the average percentage biodegradation by BOD and that of the test item analytically were 2% and 0%, respectively. The test item was not readily biodegradable under the test conditions

Description of key information

The study evaluated the biodegradability of HES 10108 by microorganisms and the study was conducted according to OECD Guidelines 301C and Method for Testing the Biodegradability of Chemical Substances by Microrganisms stipulated in the Testing Methods for New Chemical Substances, Japan and in accordance with the Principles of GLP. The conditions of incubation were-

Concentration of test item - 100 mg/l

Concentration of activated sludge - 30 mg/l (as concentration of suspended solids)

Volume of test solution - 300 ml

Incubation temperature - 25 ± 1 °C

Incubation duration - 28 days (under dark condition)

Biodegradation was measured by estimating the BOD and analytically by measuring the concentration of the test item using validated HPLC methods.

Under the conditions of the study, the average percentage biodegradation by BOD and that of the test item analytically were 2% and 0%, respectively. The test item was not readily biodegradable under the test conditions

Key value for chemical safety assessment

Biodegradation in water:

under test conditions no biodegradation observed

Type of water:

other: activated sludge