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Diss Factsheets
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EC number: 202-544-6 | CAS number: 96-91-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1983
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- significant methodological deficiencies
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 983
Materials and methods
- Principles of method if other than guideline:
- Picramic Acid was evaluated in 144 h LC, and EC, studies using American oysters (C. virginica). The nominal test concentrations of Picramic Acid were 0, 15, 25, 35, and 75 mg/L.
Test solutions were renewed every 24 h.
Both mortality and the amount of shell deposition were used to measure toxicity.
The duration of the study, 144 h, was adequate for sufficient shell deposition. At the end of 144 h, LC, no growth EC, and shell deposition EC,, were calculated - GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-amino-4,6-dinitrophenol
- EC Number:
- 202-544-6
- EC Name:
- 2-amino-4,6-dinitrophenol
- Cas Number:
- 96-91-3
- Molecular formula:
- C6H5N3O5
- IUPAC Name:
- 2-amino-4,6-dinitrophenol
1
- Specific details on test material used for the study:
- Picramic acid (lot number 38C-0117) was purchased from the Sigma Chemical Company (St. Louis, Missouri),
Sampling and analysis
- Details on sampling:
- One replicate of 2 oysters was tested at each concentation because sufficient dissolved oxygen (>8.0 mg/L) was available due to the air-lift system. Test solutions were renewed every 24 h.
Test organisms
- Test organisms (species):
- other: American oysters (C. virginica).
Study design
- Test type:
- static
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 10.5 (+ 0.0)
- pH:
- 7.6 (+ 0.04)
- Dissolved oxygen:
- 8.6 (+ 0.52)
- Salinity:
- 7.0 (5 0.23)
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 144 h
- Dose descriptor:
- LC50
- Effect conc.:
- 69.8 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Key result
- Duration:
- 144 h
- Dose descriptor:
- EC50
- Effect conc.:
- 22.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Remarks:
- no growth EC,
- Details on results:
- The 144 h LC, for Picramic Acid was 69.8 mglL, and the 144 h no growth EC, was 22.5 mg/L. The shell deposition EC, for Picramic Acid was 5.6 mg/L
Applicant's summary and conclusion
- Conclusions:
- The 144 h LC, for Picramic Acid was 69.8 mglL, and the 144 h no growth EC, was 22.5 mg/L. The shell deposition EC, for Picramic Acid was 5.6 mg/L
- Executive summary:
The toxicity of Picramic Acid was evaluated in 144 h LC, and EC, studies using American oysters (C. virginica).
The 144 h LC, for Picramic Acid was 69.8 mglL, and the 144 h no growth EC, was 22.5 mg/L. The shell deposition EC, for Picramic Acid was 5.6 mg/L
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