Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
adsorption / desorption: screening
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
2.13
Temp.:
23 °C
pH:
6.077
Remarks on result:
other: Value is weighted average of constituent ranges.
Details on results:
Approximately 14 peaks were determined with peak areas ranging from 0.89 to 19.47%.

The Log Kow values of the test substance was:

72% of peaks have a Log Kow in the range < 0.3 to 2.03.

20% of peaks have a Log Kow in the range 2.98 to 4.49.

8% of peaks have a Log Kow in the range 4.69 to 6.21.

The weighted average Log Kow of the above values was 2.13. The majority of the peak areas had Log Kow values < 2.03.

Conclusions:
The substance is a UVCB and as such ranges of Log Kow values were provided. The weighted average of the Log Kow values of the various peaks was determined to be 2.13 at 23°C.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion