Registration Dossier
Registration Dossier
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EC number: 944-886-5 | CAS number: -
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (3 weeks, reproductive impairment) = 60000 μg/l - strontium
EC50 (3 weeks, reproductive impairment) = 125000 μg/l - magnesium
Key value for chemical safety assessment
Additional information
The long-term toxic potential of the substance is evaluated by considering data on similar substances. Justification for Read Across is given in Section 13 of IUCLID.
The chronic toxicity of the metal ions to Daphnia magna were evaluated after the exposure of the organisms to the substances for 3 weeks. Twenty daphnids divided in four test chambers were exposed to concentrations ranging from 5 to 12 depending on the toxicant and the initial effects observed. A geometric series of concentrations was used for obtaining an approximation of toxicity; a linear series of concentrations was often used for delineating reproductive impairment levels. After the concentrations to be tested were determined, three to seven tests were run for each toxicant. At metai concentrations permitiing survival but impairing reproduction, daphnids weighed less than control animals. The decrease (16 % and 50 %) in the number of young born (reproductive impairment) and the LC50 were evaluated.
Decrease in animal weight and increase in the percentage of protein per animal and on GOT activity was notably greater with Magnesium and Strontium addition.
16 % reproductive impairment = 82000 μg/l (nominal), 50 % reproductive impairment = 125000 μg/l (nominal), LC50 = 190000 μg/l (nominal) - magensium
16 % reproductive impairment = 42000 μg/l (nominal), 50 % reproductive impairment = 60000 μg/l (nominal), LC50 = 86000 μg/l (nominal) - strontium
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