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Physical & Chemical properties

Melting point / freezing point

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Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
Haematoxylin
EC Number:
208-237-3
EC Name:
Haematoxylin
Cas Number:
517-28-2
Molecular formula:
C16H14O6
IUPAC Name:
haematoxylin

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
>= 267 °C
Atm. press.:
ca. 1 013 hPa
Decomp. temp.:
ca. 267 °C
Remarks on result:
not determinable

Any other information on results incl. tables

A first pre-test was conducted and the test item appeared to be degraded at the end of measurements. To determine if peaks observed during this pre-test correspond to thermal degradation and not to transition phases, three more tests were performed and corresponding thermograms were obtained. Moreover the crucible was observed and opened at the end of each trial and the appearance of the test item was checked.

A first peak was observed near 140°C and seems to correspond with the boiling of the water contained in the test item as a mass loss of about 5.3% is observed and comply with the quantity of water (5.3%) given by the certificate of analysis.

A second peak was observed near 210°C. It seems the test item under powder form melts at this temperature and becomes “vitrified”. However, if the test item is cooled and then heated again, the transition peak is no longer observed.

A third peak is observed near 267°C and corresponds to the degradation of the test item. The test item changes into a black carbonised powder. In addition the test item mass decreases and thus indicates an emission of volatile compounds during the degradation process.

Moreover, the melting point of the Indium respects the checking cards limits (156.6°C for a reference value of 156.6°C) so as its enthalpy (29.31 J/g for a reference value of 28.6 J/g).

Applicant's summary and conclusion

Conclusions:
No melting point or boiling point of the substance were observed up to 267°C as the test item starts to degrade at this temperature.
However, the following observations can be noticed. The water contained into the test item vaporizes near 140°C. The test item is “vitrified” near 210°C.
Executive summary:

No melting point or boiling point of the substance were observed up to 267°C as the test item starts to degrade at this temperature.

However, the following observations can be noticed. The water contained into the test item vaporizes near 140°C. The test item is “vitrified” near 210°C.

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