Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 947-724-1 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Based on a read-across from an experimental GLP study performed on the analogue substance Cistus concrete according to the OECD 301F guideline, the registered substance is considered to be not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
A reliable study on the registered substance was not available. Therefore, in order to assess the ready biodegradability of the registered substance, the results from an experimental GLP study performed on the analogue substance Cistus concrete have been used.
In this study, the test item Cistus concrete was investigated for its ready biodegradability in a manometric respirometry test over a period of 28 days, according to the OECD 301F guideline, further extended to 60 days.
The test item was exposed to aerobic activated sludge from the aeration tank of a domestic waste water treatment plant. The biodegradation was followed by the oxygen uptake of the microorganisms during exposure. As a reference item sodium benzoate was tested simultaneously under the same conditions as the test item, and functioned as a procedure control.
The 10-day window started at day 3, when the mean biodegradation was 11%. At the end of the 10-day window at day 13, the mean biodegradation was 33%. After 28 days the mean biodegradation of Cistus Concrete was 49% (ThODNH4); the 10 day window criterion was not passed.
Therefore, Cistus Concrete is considered to be not readily biodegradable.
The test was extended to 60 days, as no plateau was reached within 28 days. The biodegradation was 52% at the end of the test at day 60.
The reference item sodium benzoate was sufficiently degraded, thus confirming the suitability of the aerobic activated sludge inoculum used.
In addition, the test item was assumed to be not inhibitory to the aerobic activated sludge microorganisms because degradation was >25% within 14 days in the toxicity control.
The validity criteria were successful and the study respected the requirements of the guideline. This study was therefore considered acceptable for that endpoint and the read-across justification is provided in the iuclid study record.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
