Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Genetic toxicity in vivo

Description of key information

Although other registrants and government / non-government reviews have concluded negative for titanium salts, it is worth noting that a number of publications exist showing positive effects from in-vitro testing of nano-particulates. However, no mechanisms for toxicity have been identified.

A respresentative sample of publications are included as weight of evidence.

Additional information

Justification for classification or non-classification