Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22.-28.09.2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
no
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
3-Fluor-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl-4-boronic acid
EC Number:
620-455-4
Cas Number:
524709-74-8
Molecular formula:
C21 H26 B F O2
IUPAC Name:
3-Fluor-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl-4-boronic acid

Results and discussion

Water solubility
Key result
Water solubility:
< 0.182 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
5.8

Applicant's summary and conclusion

Executive summary:

The water solubility of the test substance is below < 0.182 mg/L.