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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-04-11
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
1.8
Temp.:
25 °C
pH:
5

 
   tR,min Area %   log Pow  Weighted average log Pow,peaks > 5 %
 Injection 1 2,39  18,5  0,74  1,76
   2,60  28,5 1,41   
  2,85   9,5 1,89   
  3,18   15,2 2,32   
   3,63 6,1   2,73  
   4,15 10,6   3,07  
   5,09 2,7   2,50  
   5,94 3,9   3,79  
   6,26 1,7   3,89  
   7,67 1,0   4,22  
   9,15 2,3   4,49  
 Injection 2 2,39   19,1 0,74   1,75
   2,60 28,8   1,42  
   2,85 8,3   1,90  
   3,19 14,6   2,33  
   3,64 5,9   2,74  
   4,16 10,6   3,07  
   5,10 2,7   3,51  
  5,96   4,5 3,80   
   6,29 1,9   3,89  
   7,71 1,0   4,23  
   9,19 2,6   4,50  
 Average value        1,76
         
Conclusions:
Weighted average: Log pow: 1.8 @ 25°C
Executive summary:

Weighted average: Log pow: 1.8 @ 25°C

Description of key information

Weighted average: Log pow: 1.8 @ 25°C

Key value for chemical safety assessment

Log Kow (Log Pow):
1.8
at the temperature of:
25 °C

Additional information