ε-Caprolactone, oligomeric reaction products with 2,2'-oxydiethanol

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-04-11

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

Deviations:

no

GLP compliance:

no

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Analytical method:

high-performance liquid chromatography

Key result

Type:

log Pow

Partition coefficient:

1.8

Temp.:

25 °C

pH:

5

tR,min Area %   log Pow  Weighted average log Pow,peaks > 5 %  Injection 1 2,39  18,5  0,74  1,76    2,60  28,5 1,41      2,85   9,5 1,89      3,18   15,2 2,32       3,63 6,1   2,73      4,15 10,6   3,07      5,09 2,7   2,50      5,94 3,9   3,79      6,26 1,7   3,89      7,67 1,0   4,22      9,15 2,3   4,49    Injection 2 2,39   19,1 0,74   1,75    2,60 28,8   1,42      2,85 8,3   1,90      3,19 14,6   2,33      3,64 5,9   2,74      4,16 10,6   3,07      5,10 2,7   3,51     5,96   4,5 3,80       6,29 1,9   3,89      7,71 1,0   4,23      9,19 2,6   4,50    Average value        1,76

Conclusions:

Weighted average: Log pow: 1.8 @ 25°C

Executive summary:

Weighted average: Log pow: 1.8 @ 25°C

Description of key information

Weighted average: Log pow: 1.8 @ 25°C

Key value for chemical safety assessment

Log Kow (Log Pow):

1.8

at the temperature of:

25 °C