Reaction mass of 2-hydroxy-N-(2-(2-hydroxyethoxy)ethyl)-N-(2-hydroxyethyl)-N-methylethan-1-amininium hydroxide and 2-hydroxy-N,N-bis(2-hydroxyethyl)-N-methylethanaminium hydroxide

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

08 November 2017 to 05 April 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

30 May 2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

27 July 1995

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

method to determine freezing temperature

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: D26-3-3-1
- Expiration date of the lot/batch: 01 December 2018
- Purity test date: 11 April 2017
- Stability under test conditions: Room temperature, in the dark
- Purity: 47.4%

Key result

Melting / freezing pt.:

< -20 °C

Remarks on result:

other: The test item became increasingly viscous during cooling.

Conclusions:

The freezing point of the test item has been determined to be less than -20 °C (<253 K).

Description of key information

A K1, GLP-compliant study was performed according to a method compatible with OECD guideline 102 and EU Method A.1. The freezing point of the test substance was determined to be <-20 °C or < 253 K (Covance, 2019).

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

-20 °C

Additional information

The freezing point was determined to be <-20 °C.