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EC number: 202-902-1 | CAS number: 100-93-6
% Tissue Viability
% Tissue viability (tissue 1)
% Tissue viability (tissue 2)
% Tissue viability (tissue 3)
% Tissue viability (mean)
± SD of mean tissue viability (%)
OD of negative control
≥0.8 and≤ 2.8
% tissue viabilityof positive control SDS
£20% of negative control
SD of mean viability of the
tissue replicates (%)
1.6% (negative control)0.2% (positive control)1.5% (test item)
Two experiments were performed.
The first experiment was not valid, because the standard deviation of the three replicates of the test item was 18.5%, required is ≤18%. This experiment is not reported in this report, but the raw data are kept in the GLP- archive of the test facility.
After the treatment, the mean value of relative tissue viability was reduced to 99.9%. This value is above the threshold for skin irritation (50%).
The test item N-(4-anilinophenyl)-4-methylbenzenesulfonamide is considered as non-irritant to skin.
The optical density of the negative control was well within the required acceptability crite-rion of 0.8 ≤ mean OD ≤ 2.8.
The positive control has met the acceptance criterion too, for thus ensuring the validity of the test system.
Variation within replicates was within the accepted range for negative control, positive control and test item (required: ≤ 18%).
For these reasons, the result of the test is considered valid.
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