Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Remarks:
laser diffraction test
Type of information:
experimental study
Adequacy of study:
key study
Study period:
November 2017 - February 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Qualifier:
according to guideline
Guideline:
other: IPAC MT 187 “Particle Size Analysis by Laser Diffraction”, Handbook K,
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle

Test material

Constituent 1
Chemical structure
Reference substance name:
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
Cas Number:
571188-59-5
Molecular formula:
C14H22N4O2
IUPAC Name:
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
Test material form:
solid: bulk

Results and discussion

Mass median aerodynamic diameter:
ca. 64.53 µm
Geometric standard deviation:
ca. 0.8
Particle sizeopen allclose all
Key result
Percentile:
D10
Mean:
< 14.793 µm
St. dev.:
0.222
Key result
Percentile:
D50
Mean:
< 64.53 µm
St. dev.:
0.181
Key result
Percentile:
D90
Mean:
< 148.458 µm
St. dev.:
1.716

Any other information on results incl. tables

Average**

Volume weighted mean       74.432

Median                               64.530

Mode                                 82.545

MMAD *                           71.567

d10 - 10 % of material is < 14.793

d50 - 50 % of material is < 64.530

d90 - 90 % of material is < 148.458

All results are in μm

* Mass median aerodynamic diameter

** Average result is calculated from the entirety of data captured in each run and is not a simple

arithmetic mean.

Applicant's summary and conclusion

Conclusions:
Average** % STDVP
d10 - 10 % of material is < 14.793 1.5
d50 - 50 % of material is < 64.530 0.3
d90 - 90 % of material is < 148.458 1.2