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EC number: 287-094-9 | CAS number: 85409-27-4
No mortality, no clinical signs, body weight gain normal, no treatment related changes on macroscopic examination.
This data is being read across from the source study that tested Rosin, fumarated, reaction products with formaldehyde based on category read across that is explained in the category justification document attached in Section 13 of the dossier.
In an acute oral toxicity study, a single dose of rosin, fumarated, reaction products with formaldehyde was administered via gavage to six female rats were at a concentration of 2000 mg/kg. No mortality occurred and there were no treatment-related signs of toxicity. The acute oral LD50 in this study was >2000 mg/kg bw for female rats.
In an acute oral toxicity study, a single dose of rosin, fumarated, reaction products with formaldehyde was administered via gavage to sixfemale rats were at a concentration of 2000 mg/kg. No mortality occurred and there were no treatment-related signs of toxicity. The acute oral LD50 in this study was >2000 mg/kg bw for female rats.
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